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Varied Clinical Presentations of Congenital Syphilis in Infants: A Case Series of 7 Cases |
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KS Sanjay, Usha Bangalore Kantharajanna, Ratakonda Sruthi, Chandana Kalavala 1. Professor and Director, Department of Paediatrics, IGICH, Bangalore, Karnataka, India. 2. Associate Professor, Department of Paediatrics, SABVMCRI, Bangalore, Karnataka, India. 3. Assistant Professor, Department of Paediatrics, MSRMCRI, Bangalore, Karnataka, India. 4. Senior Resident, Department of Paediatrics, IGICH, Bangalore, Karnataka, India. |
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Correspondence Address : Usha Bangalore Kantharajanna, No. 22, 4th Main, 10th Cross End, Arekempanahalli Layout, Wilson Garden, Bengaluru-560027, Karnataka, India. E-mail: ushasumuk@gmail.com |
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| ABSTRACT |  | ||||||
: Congenital Syphilis (CS), also known as mother-to-child transmission of syphilis is caused by Treponema pallidum. Infected pregnant women can transmit the infection vertically to the foetus. Diagnosis of CS can be difficult because more than two-thirds of affected infants remain asymptomatic at birth, and signs may be non-specific or subtle. In this case series, seven cases of CS with varied presentations are described. In cases 1, 2, 6, mothers were screened after the baby was tested positive for Venereal Disease Research Laboratory (VDRL) test. In two cases (Case-4,6), the mothers received inadequate treatment for syphilis antenatally. In the present case series, Case-6 presented with renal manifestations early in the course of the disease, Case-2 had skin manifestations like vesicular lesions and peeling of skin and Case-7 had symptoms suggestive of meningitis. Because of its varied presentations, high index of suspicion is the key to diagnosis and treatment of CS and prognosis. Screening of pregnant women and treating them is the most effective way in preventing CS and its related morbidity and mortality. | |||||||
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| Keywords : Meningitis, Renal manifestations, Venereal disease research laboratory, Vesicular lesions | |||||||
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DOI and Others :
DOI: 10.7860/IJNMR/2023/62969.2398
Date of Submission: Jan 18, 2023 Date of Peer Review: Mar 22, 2023 Date of Acceptance: Aug 04, 2023 Date of Publishing: Dec 31, 2023 AUTHOR DECLARATION: • Financial or Other Competing Interests: None • Was informed consent obtained from the subjects involved in the study? Yes • For any images presented appropriate consent has been obtained from the subjects. Yes PLAGIARISM CHECKING METHODS: • Plagiarism X-checker: Jan 27, 2023 • Manual Googlin |
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