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Year :2014
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Month :
July
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Volume :
2
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Issue :
1
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Page :
1 - 6
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Clinico-bacteriological Profile of Neonates Born with Risk Factors of Septicemia
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Correspondence Address :
Priyamvada Roy, Ashwani Kumar, MMA Faridi, Iqbal R Kaur, Bineeta Kashyap,
Dr. Priyamvada Roy,
Care of Group Captain DD Roy, Flat Number C-115,
Jalvayu Vihar (Near AWHO), Plot Number 8, Pocket
P-4, Builder’s Area, Greater Noida-201310, Uttar
Pradesh, India.
Phone: 9953820283
Email: priyamvadaroy@yahoo.in
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Background: Septicemia is the single most important cause of neonatal morbidity and mortality in the world, accounting for over half of the cases. Aim: This study was conducted to establish the clinical and bacteriological profile in newborns with risk factors of septicemia. Subjects and Methods: One hundred and fifty consecutive neonates delivered with risk factors of septicemia were recruited after obtaining informed consent. Blood culture was done using BACTEC PEDS PLUS/F CULTURE vials as a part of sepsis screen used to diagnose septicemia. In addition acute phase reactants like total leucocyte count and C-reactive protein measurements were also documented. Statistical analysis: Correlation of all risk factors with laboratory findings was obtained by using Pearson chi-square test and Fisher’s exact test. p-value of less than 0.05 was considered as significant. Results: Blood culture positivity was found in 28% neonates born with risk factors of septicemia out of which 57.1% were gram-positive and 42.9% were gram-negative isolates respectively. Staphylococcus aureus being the most common among the gram-positive bacteria, was isolated in 19 (45.2%) of cases. Among the gram-negative bacteria, Acinetobacter baumannii was the most common being present in 13 (30.9%) of cases. Among all the risk factors studied, fever in the mother was significantly correlating with positive sepsis screen. Conclusion: Blood culture positivity increases with increase in number of risk factors in neonatal septicemia. Hence screening tests for septicemia must be done routinely in such cases.
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