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Tracheo-oesophageal Fistula with Partial Pulmonary Agenesis, Broncho-oesophageal Fistula, and Gastric Duplication in a Neonate: A Case Report on the Spectrum of Aberrations in Foregut Embryogenesis |
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Neel Aggerwal, Umesh B Singh, Sheetal Upreti 1. Additional Professor, Department of Paediatric Surgery, Post Graduate Institute of Child Health, Noida, Uttar Pradesh, India. 2. Associate Professor, Department of Paediatric Surgery, Post Graduate Institute of Child Health, Noida, Uttar Pradesh, India. 3. Assistant Professor, Department of Paediatric Surgery, Post Graduate Institute of Child Health, Noida, Uttar Pradesh, India. |
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Correspondence Address : Dr. Umesh B Singh, Associate Professor, Department of Paediatric Surgery, Post Graduate Institute of Child Health, Noida-201310, Uttar Pradesh, India. E-mail: singhub.2008@gmail.com |
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| ABSTRACT |  | ||||||
: An erroneous connection between the trachea and oesophagus is the hallmark of Tracheo-Oesophageal Fistula (TEF), a congenital disorder that can provide serious complications for newborn care. TEF results from a defect in foregut embryogenesis that interferes with the trachea and oesophagus’s natural separation during foetal development. Since, it frequently co-exists with other congenital conditions such as anorectal malformations, cardiac problems or skeletal abnormalities, early identification and interdisciplinary care are essential for the best results. A 36-week-old preterm low birth weight male neonate presented within 12 hours of birth, having respiratory distress, diagnosed as TEF, detected to have a rare combination of multiple congenital anomalies related to foregut development like partial pulmonary agenesis, bronchoesophageal fistula and gastric duplication in a preterm male neonate. The complexity of this presentation required coordinated surgical interventions including thoracotomy, oesophagostomy and excision of a gastric duplication cyst. To the greatest extent of the information, this was the first human case of its sort to be documented in the literature, exhibiting three foregut development abnormalities: gastric duplication, partial pulmonary agenesis and bronchooesophageal fistula. In the present case, the gastric duplication cyst was surgically removed during the TEF repair, highlighting the need of treating all abnormalities thoroughly to get better results. This case highlights the challenges and management strategies in addressing multiple anomalies in neonates with TEF. | |||||||
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| Keywords : Congenital anomalies, Foregut embryological anomalies, Intestinal duplication, Oesophageal atresia | |||||||
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DOI and Others :
DOI: 10.7860/IJNMR/2025/76919.2450
Date of Submission: Nov 21, 2024 Date of Peer Review: Mar 05, 2025 Date of Acceptance: Apr 18, 2025 Date of Publishing: Sep 30, 2025 AUTHOR DECLARATION: • Financial or Other Competing Interests: None • Was informed consent obtained from the subjects involved in the study? Yes • For any images presented appropriate consent has been obtained from the subjects. Yes PLAGIARISM CHECKING METHODS: • Plagiarism X-checker: Nov 22, 2024 • Manual Googling: Apr 07, 2025 • iThenticate Software: Apr 17, 2025 (8%) ETYMOLOGY: Author Origin EMENDATIONS: 6 |
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Case report
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