Original article / research
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Year :2022
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Month :
January
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Volume :
10
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Issue :
1
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Page :
PO01 - PO05
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Demographic Characteristics and Outcome of Children with SARS-CoV-2 Infection Admitted in a Tertiary Care Centre in Central India- A Retrospective Study
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Milind M Suryawanshi, Chandrakant M Bokade, Shamama Subuhi, Dipak Madavi, Priyanka M Meshram
1. Assistant Professor, Department of Paediatrics, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
2. Professor, Department of Paediatrics, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
3. Assistant Professor, Department of Paediatrics, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
4. Associate Professor, Department of Paediatrics, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
5. Assistant Professor, Department of Paediatrics, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
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Correspondence Address :
Milind M Suryawanshi, Chandrakant M Bokade, Shamama Subuhi, Dipak Madavi, Priyanka M Meshram,
Dr. Milind M Suryawanshi,
Shivneri Apt. F-13, Orange City Hospital Square, Khamala, Nagpur-440015, Maharashtra, India.
E-mail: dr.milind.suryawanshi@gmail.com
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| | | ABSTRACT |  |
: Introduction: Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) is an event of utmost importance in the medical field. It has affected the lives of millions worldwide, affecting adults more than children. But paediatric coronavirus disease is also complicated by its varied clinical presentation, difficulty in diagnosis and non availability of any rational protocol when it came to identification and management of cases.
Aim: To assess demographic characteristics and outcome of children with SARS-CoV-2 infection.
Materials and Methods: A single-centre retrospective hospital-based observational study was carried out among 150 children. Nasopharyngeal swabs were taken and tested using real-time Reverse Transcription-Polymerase Chain Reaction (RT-PCR) for SARS-CoV-2 infection to confirm Coronavirus Disease 2019 (COVID-19). The information was collected from Medical Record Department (MRD) through Case Record Form (CRF). The clinical and laboratory features of all children (age ≥1 months to ≤12 years) were selected between 1st March 2020 -31st October 2020 were noted and selected. The collected data was tabulated and all statistical analysis was done.
Results: Out of 150 children, 81 (54%) were male and 69 (46%) were female. Only 26 (17.3%) were symptomatic. In these 26, respiratory system involved 12 (46.2%) children, followed by acute febrile illness 7 (26.9%) and then neurological 3 (11.6%), gastrointestinal 2 (7.7%), haematological 1 (3.8%), and cardiovascular 1 (3.8%). Co-morbidities (thalassaemia, cerebral palsy, seizure disorder and heart disease) were present in 5 (3.3%) children, in which 3 (60%) developed moderate and severe degree of illness. The treatment was given as per the protocol developed at Institutional level from Indian Council of Medical Research (ICMR), and Ministry of Health and Family Welfare (MoHFW) guidelines. One child died and the rest were discharged.
Conclusion: Majority of the children having SARS-CoV-2 infection were asymptomatic, however, few had mild illness. Furthermore, co-morbidities were contributed for severity of illness in the children affected with SARS-CoV-2 infection which leads into more vulnerable outcome.
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Keywords :
Coronavirus disease 2019, Indian council of medical research, Real-time reverse transcription-polymerase chain reaction
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DOI and Others :
DOI: 10.7860/IJNMR/2022/51326.2321
Date of Submission: Jul 09, 2021
Date of Peer Review: Sep 23, 2021
Date of Acceptance: Dec 15, 2021
Date of Publishing: Mar 31, 2022
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yeso
• Was informed consent obtained from the subjects involved in the study? No
• For any images presented appropriate consent has been obtained from the subjects. No
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